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ea0063p25 | Adrenal and Neuroendocrine Tumours 1 | ECE2019

Management of mitotane for advanced adrenocortical carcinoma: a survey in Italy

Puglisi Soraya , Saba Laura , Perotti Paola , Calabrese Anna , Basile Vittoria , Arnaldi Giorgio , Cannavo Salvatore , Stigliano Antonio , Canu Letizia , Loli Paola , Pivonello Rosario , Malandrino Pasqualino , Badalamenti Giuseppe , Torlontano Massimo , Della Casa Silvia , Scaroni Carla , Terzolo Massimo

Background and objective: Mitotane is the main option of treatment for advanced adrenocortical carcinoma (ACC). However, limited evidence is available regarding practical management of mitotane treatment and its eventual combination with chemotherapy or radiotherapy. The aim of the study is to do a survey on the use of mitotane for advanced ACC in expert Italian centers, analyzing data of the LYSOSAFE database.Methods: Retrospective analysis of patients ...